Engitix appoints two additional international biotech industry leaders as Scientific Advisors

London, UK – 25 June 2024 – Engitix Ltd (‘Engitix’), a biotechnology company with a portfolio of drug discovery programmes in fibrosis and solid tumours using its proprietary human extracellular matrix (ECM) platform, today announces the appointment of two biotech industry leaders as Scientific Advisors: Adrian S. Ray, PhD, and Scott Turner, PhD.

These appointments support Engitix’s evolution as it harnesses its ECM platform to discover new targets and biomarkers for therapeutic benefit and advances towards clinical development.

Dr Giuseppe Mazza, CEO of Engitix said, “We are pleased to welcome Dr Adrian Ray and Dr Scott Turner as new scientific advisors. Their combined industry insights, strong translational science and small molecule and biologic drug discovery experience across cancer and fibrosis disease will enhance our R&D efforts. Their strategic guidance will be invaluable as we continue to advance discoveries from our proprietary ECM platform technologies into transformational therapies for patients with fibrosis and solid tumours.”

Dr Adrian Ray has over two decades of experience in biotech working at Gilead, Nimbus, Morphic and, most recently, serving as Chief Scientific Officer at Third Harmonic Bio. He has provided leadership for small molecule drug discovery, nonclinical development and translation across therapeutic areas contributing to numerous IND and successful worldwide registrational filings. Dr Ray completed his graduate studies in the Pharmacology Department at Yale University, having received his undergraduate degree in Molecular, Cellular and Developmental Biology from the University of California at Santa Cruz graduating with the highest honours.

Dr Adrian Ray said, "Engitix has an unparalleled understanding of the extracellular matrix. I'm excited to work with the team on leveraging their deep data set to identify new therapeutics for fibrosis and solid tumours."

Dr Scott Turner is currently the Chief Scientific Officer at Arda Therapeutics. Prior to joining Arda, Scott served as CSO at Pliant Therapeutics, where he played a pivotal role in the creation of Pliant's fibrosis discovery platform and spearheaded the development of their anti-fibrotic pipeline. His innovative approaches, including pioneering the use of single-cell data to dissect drug mechanisms of action and driving an advanced biomarker strategy, led to remarkable successes in achieving clinical proof of concept. Prior to Pliant, Dr Turner led research and development at KineMed Inc. a platform technology company developing translational biomarkers in fibrosis and metabolic disease. Dr Turner gained his PhD from the University of California, Berkeley in Nutritional Sciences and Toxicology.

Dr Scott Turner said, "In spite of recent advances, fibrosis remains a significant unmet medical need.  New strategies are needed to address this challenging problem.  I am excited to work with the Engitix team and advisors to leverage their novel ECM platform to identify new treatments."

Engitix's new scientific advisors bring extensive scientific and industry expertise and diverse perspectives that will complement and enhance the knowledge of its original eight Scientific Advisors, who are renowned global academics and clinical leaders across diseases of the gastrointestinal system, skin and lung fibrosis and cancers.

Current scientific advisors also include Professor Massimo Pinzani, MD, PhD, FAASLD, FRCP,  Alex Lugovskoy, PhD, Doug Thorburn, MD, Emmanuel Tsochatzis, MD, MSc, FEBTM, FRCP, PhD, Tu Vinh Luong, MD, FRCPATH,  Antonio Di Sabatino, MD, Hendrik-Tobias Arkenau, MD, PhD, FRCP and Giuseppe Fusai, MD. Biographies for all scientific advisors are available on Engitix’s website here.

Engitix also recently expanded its leadership team with the appointment of Matthew Edwards, PhD, as Senior Vice President of Discovery Sciences, and Emma Huang, PhD, as Vice President of Data Sciences.