SiSaf Ltd

R&D/Manufacturing

Membership category
Corporate

8 Frederick Sanger Road, Surrey Research Park, Guildford, Surrey, GU2 7YD, United Kingdom

SiSaf Ltd at a glance

SiSaf is an RNA delivery and therapeutics company. Its proprietary Bio-Courier® technology improves nucleic acid stability and transfection efficiency and the company uses the technology to develop RNA therapeutics that are principally focused on rare genetic disorders. The company also partners its delivery technology for a wide range of molecules.

About SiSaf Ltd

SiSaf is an RNA therapeutics company with a proprietary delivery platform. Its lead programs are a siRNA treatment for Osteopetrosis ADO2 and a partnered siRNA treatment for Corneal Dystrophy. The company is in the process of expanding its pipeline to other fields, including oncology.

SiSaf’s proprietary Bio-Courier® delivery platform combines organic materials with inorganic silicon to improve the stability, solubility, safety, and targeting of a wide range of molecules, including biologicals such as nucleic acids.

Unlike other delivery technologies such as lipid nanoparticles, Bio-Courier particles can be manufactured empty and nucleic acids can be introduced in a separate step, at the point of use. 

Led by founder and leading biomaterials specialist Dr. Suzanne Saffie-Siebert, SiSaf is a venture capital-backed private company. Headquartered in Guildford, UK, it has fully integrated research labs and bio-analytical facilities, a scalable technology to fast-track development, and a growing patent estate with extensive freedom to operate.

Therapeutic area(s)

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