SiSaf Ltd
R&D/Manufacturing
- Website
- https://www.sisaf.com/
- Membership category
- Corporate
8 Frederick Sanger Road, Surrey Research Park, Guildford, Surrey, GU2 7YD, United Kingdom
SiSaf Ltd at a glance
About SiSaf Ltd
SiSaf is an RNA therapeutics company with a proprietary delivery platform. Its lead programs are a siRNA treatment for Osteopetrosis ADO2 and a partnered siRNA treatment for Corneal Dystrophy. The company is in the process of expanding its pipeline to other fields, including oncology.
SiSaf’s proprietary Bio-Courier® delivery platform combines organic materials with inorganic silicon to improve the stability, solubility, safety, and targeting of a wide range of molecules, including biologicals such as nucleic acids.
Unlike other delivery technologies such as lipid nanoparticles, Bio-Courier particles can be manufactured empty and nucleic acids can be introduced in a separate step, at the point of use.
Led by founder and leading biomaterials specialist Dr. Suzanne Saffie-Siebert, SiSaf is a venture capital-backed private company. Headquartered in Guildford, UK, it has fully integrated research labs and bio-analytical facilities, a scalable technology to fast-track development, and a growing patent estate with extensive freedom to operate.