Research Associate (Fixed Term)
Milner Therapeutics Institute, University of Cambridge
The Milner Therapeutics Institute (MTI) at the University of Cambridge aims to accelerate translation of pioneering science into therapies. The newly established Functional Genomics Screening Laboratory (FGSL) at the MTI applies arrayed CRISPR screening in human cellular models to advance mechanistic understanding underlying tissue homeostasis and disease biology. Formed as a joint venture with the Medical Research Council and AstraZeneca, this new laboratory aligns with the MTI's vision of breaking the mould of how academia and industry interact. The FGSL is part of the UK Research and Innovation's Human Functional Genomics Initiative to facilitate innovative and collaborative research to drive new scientific discoveries.
We are seeking to recruit a biologist with a strong background in complex cellular modelling to join the FGSL team. You will be applying your expertise in characterising physiological-relevant models such as organoids, primary cells, co-cultures or stem cells to design and implement arrayed CRISPR screens. The ideal candidate is proficient in developing a range of functional assays such as imaging and flow cytometry to identify key phenotypes suitable for high-throughput screening. Previous experience in utilising automated or semi-automated liquid handlers for microplate-based assays is highly desirable.
This is a highly collaborative role where you will work closely with scientists and bioinformaticians from the MTI, AstraZeneca, small/medium enterprises and academic institutions. You will have the opportunity to develop new skills in areas including multi-modality screens, automation platform and bioinformatics analysis.