PDRA in Quantitative Imaging Biology (10360)
Rosalind Franklin Institute
We are currently seeking a Postdoctoral Research Associate to join our dynamic laboratory at the Rosalind Franklin Institute. If you are a creative scientist that want to explore novel venues on quantitative imaging biology, join us. The Pombo-Garcia lab is interested in Molecular Organisation of Cell Interfaces in the epithelial tissue and in pathology of intestinal diseases. We use super-resolution STED microscopy in combination with gut organoids, biophysics & chemical biology to uncover how epithelial cells organise in space and time under different physico-chemical environments to drive self-organisation processes that shape mesoscale structures enabling tissue function. To that end, we generate high amount of complex data across scales from molecules to mesoscale structures. Our interdisciplinary team includes biology, chemistry and physics.
The Franklin is building technologies to enable imaging molecules of interest in the context of disease in their native state, using electron microscopy, light and super-resolution correlative approaches. We provide cutting-edge infrastructure to develop and implement next generation tools to advance basic science and discovery of novel therapeutics. Your role will be to lead a research project focused on quantitative imaging of epithelial cell biology and biophysics. Moreover, to support and develop novel workflows of bioimaging analysis to quantify advanced imaging data generated by super-resolution STED microscopy, FLIM, FRET and FCS. You will collaborate with other research institutions including the University of Oxford.